In December 2023, the U.K. government announced the creation of a new office focused on enforcing trade sanctions. Companies with a U.K. nexus will face higher risk of civil and criminal proceedings over sanctions compliance when the Office of Trade Sanctions Implementation (OTSI) launches later in 2024. During a seminar on OTSI’s future role and significance, organized by the Practising Law Institute, experts in the field discussed what companies can expect when OTSI launches. This article distills some of the issues they highlighted from a business and compliance perspective. See “Five Ways to Use Existing Resources to Meet Sanctions and Export Control Compliance Needs” (Apr. 10, 2024).